The Desura site’s blog has an update on the Linux client for the community-driven digital distribution service:
At initial release, Desura will simply be a small binary file to download from Desura, which may be compressed, or in some sort of signed package (yet to be decided). You place this binary anywhere on your system that you have write permissions, and when you run it, it will build the Desura folder around itself and download any remaining components.
Additional logistics regarding binary versions and game installation are elaborated on as well. You can view the breakdown of currently supported games here!